Diagnosis:
Prostate, Nerve Sparing Prostectomy with Pelvic Lymph Node Dissection:
Infliltrating Adenocarcinoma of the Prosate
- Gleason Score 3+2=5
- Pathologic Stage T2, N0, M0
- Tumor is NOT identified in the margin of resection
- Tumor measures 1.5 cm and is confined to the left lobe
- Capsular Invasion is NOT identified.
- Angiolymphatic invasion is NOT identified
- Focal Perineural Invasion is identified
- Mulitfocal PIN is identied
- Ten (10) of ten (10) pelvic lymph nodes are negitive for metastatic adenocarcinoma.
- Right and Left Seminal Vesicle are negitive for tumor.
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* - 12 ng/dl
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| * -3.9
|_*________*____*____*___*-0.0 ng/dl
more imagesTotal Serum PSA - 0.0 ng/dl.
Major prognostic markers for patients status post radical prostectomy for prostatic adenocarcinoma include pathologic stage, Gleason grade and Total Serum PSA levels.
Experimental/non-routine prognostic markers include DNA ploidy, p53 tumor suppressor gen, bcl-2 proto-oncogen, Ki-67 and MIB-1 (markers of increase proliferation), proteoglycan concentration studies. For informaton about these studies please contact the Department of Pathology
Search of our database finds 39 males, age 70-75, with similar Surgical Pathology findings (Stage 2B, Gleason 3+2=5) that have had undetectable Serum PSA one year after Radical Prostectecomy. 89% have had no evidence of recurrence with a average followup time of 2.2 years (1.1 - 5.0 years).
This patient had moderately differenciated adenocarcinoma that did not invade the capsule, had no angio-lymphatic invasion and was completely removed. Serum PSA has been undetectable for one year post surgery. Laboratory data indicate that this pateint has a very high likelyhood of cure. Laboratory data needs to be combined with all clinical data to generate a complete clinical picture. Continued Annual Total Serum PSA levels are recommended.