|
Table 4
Drugs Established as Human Carcinogens
| Drug | Malignancy |
| Radioactive Drugs (phosphorous, radium,
mesothorium, thorium dioxide) | Organs where concentrated
(acute leukemia, osteosarcoma, nasal sinus carcinoma,
angio-sarcoma
of the liver) |
| Arsenic | Skin Cancer |
| Methoxypsoralen | Skin Cancer |
| Phenacetin-containing Drugs | Renal Pelvis
Carcinoma, Bladder Cancer (?) |
| Alkylating Agents (melphalan, cyclophosphamide,
chloroambucil, dihydroxybusulfan and others) | Acute
Nonlymphocytic Leukemia, Bladder (cyclophosphamide), Other
Sites (?) |
| Immunosuppressive Agents (Azathioprine) |
Lymphoma
,
Skin Cancer, Soft Tissue Carcinoma, Melanoma (?), Liver and
Gall Bladder (?), Lung Adenocarcinoma (?) |
| Androgen-anabolic Steriods | Hepatocellular
Carcinoma |
Estrogen-containing Drugs
Prenatal (DES),
Postnatal (DES, conjugated estrogens, oral contraceptives) |
Vaginal Adenocarcinoma
Endometrial Carcinoma, Breast Cancer (?), Cervical
Cancer (?), Ovarian Cancer (?), Choriocarcinoma (?),
Melanoma (?), Liver Tumors (benign) |
|
